Dr. Ron’s Research Review – October 5, 2016

©                                                                                                                                                        

This week’s research review focuses on fluoride and diabetes in the US

A study investigated the hypothesis that added water fluoridation has contributed to diabetes incidence and prevalence in the United States. The findings suggest that a 1 mg increase in the county mean added fluoride significantly positively predicts a 0.23 per 1,000 person increase in age-adjusted diabetes incidence (P < 0.001) and a 0.17% increase in age-adjusted diabetes prevalence percent (P < 0.001), while natural fluoride concentration is significantly protective. For counties using fluorosilicic acid as the chemical additive, both outcomes were lower: by 0.45 per 1,000 persons (P < 0.001) and 0.33% (P < 0.001), respectively. These findings are adjusted for county-level and time-varying changes in per capita tap water consumption, poverty, year, population density, age-adjusted obesity and physical inactivity and mean number of years since water fluoridation started. Sensitivity analyses revealed robust effects for both types of fluoride. Community water fluoridation is associated with epidemiological outcomes for diabetes. (Fluegge, 2016)
Among the three fluoridation chemicals used in this data set (sodium fluoride, fluorosilicic acid, or sodium fluoro-silicate), only fluorosilicic acid was significantly and robustly associated with decreases in incidence and prevalence of diabetes.

Naturally hard water may contain greater amounts of inorganic fluoride minerals, such as fluorite (CaF2)), which are not as well absorbed when compared to sodium fluoride (NaF). Hard water is also indicative of the presence of higher levels of magnesium, which may itself offer protection from developing diabetes

“Disclaimer. The CDC’s portal for My Water’s Fluoride and the data it contained changed after the original data used in this analysis was downloaded in April 2015. Currently accessible portal data (including data from 2011 and after) is not reflective of the data used in this analysis.”

 

Dr. Ron


 

Articles

Community water fluoridation predicts increase in age-adjusted incidence and prevalence of diabetes in 22 states from 2005 and 2010
            (Fluegge, 2016) Download
Community water fluoridation is considered a significant public health achievement of the 20th century. In this paper, the hypothesis that added water fluoridation has contributed to diabetes incidence and prevalence in the United States was investigated. Panel data from publicly available sources was used with population-averaged models to test the associations of added and natural fluoride on the outcomes at the county level in 22 states in the years 2005 and 2010. The findings suggest that a 1 mg increase in the county mean added fluoride significantly positively predicts a 0.23 per 1,000 person increase in age-adjusted diabetes incidence (P < 0.001) and a 0.17% increase in age-adjusted diabetes prevalence percent (P < 0.001), while natural fluoride concentration is significantly protective. For counties using fluorosilicic acid as the chemical additive, both outcomes were lower: by 0.45 per 1,000 persons (P < 0.001) and 0.33% (P < 0.001), respectively. These findings are adjusted for county-level and time-varying changes in per capita tap water consumption, poverty, year, population density, age-adjusted obesity and physical inactivity and mean number of years since water fluoridation started. Sensitivity analyses revealed robust effects for both types of fluoride. Community water fluoridation is associated with epidemiological outcomes for diabetes.

 

References

Fluegge, K (2016), ‘Community water fluoridation predicts increase in age-adjusted incidence and prevalence of diabetes in 22 states from 2005 and 2010’, J Water and Health, 14 (4), PubMed: